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Therapeutic Use Exemptions (TUEs)

Accessing Critical Medication while Competing Clean

What are TUEs?

In some situations, an athlete may have an illness or condition that requires the use of medication listed on the World Anti-Doping Agency’s Prohibited List. USADA can grant a Therapeutic Use Exemption (TUE) in these situations in compliance with the World Anti-Doping Agency International Standard for TUEs. The TUE application process is thorough and designed to balance the need to provide athletes access to critical medication while protecting the rights of clean athletes to compete on a level playing field.

Emergency Treatment or Emergency Surgery?

Please seek medical care prior to submitting a TUE or TUE Pre-Check Form. Keep any medical documents received during care and check medication status on Global DRO.

Please review the Surgery Checklist for a detailed list of information regarding emergent/non-emergent situations.

Compare Your Global DRO Results

Using the Global DRO results for each substance, compare your findings to the table below to see if a TUE is necessary. If you have any questions regarding the necessity of a TUE, please fill out and submit the TUE Pre-Check Form below or contact USADA.

Global DRO Results TUE Instructions
In-Competition  Out-of-Competition Registered Testing Pool (RTP), Clean Athlete Program (CAP), and Education Pool (EP) Athletes All Other Athletes
Not Prohibited Not Prohibited STOP HERE – A TUE is not required for this substance. STOP HERE – A TUE is not required for this substance.
Prohibited Not Prohibited A TUE is required to use or have this substance in your system during the in-competition period. Please fill out the TUE Pre-Check Form below.
Prohibited Prohibited A TUE is required to use this substance at any time. Please fill out the TUE Pre-Check Form below.
Conditional Conditional Please read the “Additional Info” section on your GlobalDRO search results to determine if a TUE is needed. Please fill out the TUE Pre-Check Form or contact USADA if you need clarification on the conditions.

If a recommended medication is prohibited, athletes are required to take precautions to not only meet their medical needs but also abide by the anti-doping rules. Athletes in the Registered Testing Pool (RTP), Clean Athlete Program (CAP), and Education Pool (EP) require a TUE in advance of the use of a prohibited substance or method. All other athletes, including recreational athletes, should submit a TUE Pre-Check Form to USADA to determine if a TUE is required.

Please complete and submit the form below to determine if you need to apply for a TUE for your medication in question. A copy of this form will be sent to the email address entered below. If you do not receive a copy, please check your spam folder and/or resubmit the form and verify the email address is correct. Once this form is submitted successfully, you will receive a response from the USADA TUE and Drug Reference Department within 3-5 business days.

**PLEASE NOTE THAT IT MAY TAKE 3-5 BUSINESS DAYS TO RECEIVE A RESPONSE.**

Section 1: Athlete Information

Athlete Name(Required)
Sex Assigned at Birth:
Please verify that your email address is correct as a copy of this form will be sent to you.
Please include area code
To select more than one sport, hold Ctrl or list other sports in the field below.

Section 2: TUE Pre-Check Questions

Please answer the following questions by filling in the blanks or selecting "Yes," "No," or "Not Sure."

Please list all prohibited or conditional substances and medications you are currently taking. Please include the substance, dosage, route of administration, and frequency of the medications. Example: Albuterol (90mcg, inhaled, two puffs daily). You can check the status of your medication at Global DRO.

Have you received any intravenous (IV) infusion or injection greater than a total volume of 100mL in 12 hours?
Start and End Date of Treatment

Global DRO Reference Number(s) You can get a Global DRO Reference Number by checking the status of your medication on Global DRO.

1. Are you an International OR National Level Athlete? (defined above)
2. Are you entered in an International Event in the Open/Elite category? (defined below)
Include Event Name(s) and Date(s)
3. Do you have an Elite/Professional membership/license or hold an active membership for any International Federation (IF) OR National Governing Body (NGB)?
3a. If Yes in question 3 above, please provide your membership number and status below:
4. Are you registered to compete as a Professional Athlete in any event?
4a. If Yes in question 4 above, please provide event name(s) and date(s):
5. Have you ever been in a Whereabouts Information Pool for USADA or any other Code Signatory Sport Organization?
6. Have you ever officially represented the USA in an International Event?
6a. If Yes in question 6 above, please provide event name(s) and date(s):
7. Have you ever won an International or National Championship in ANY category?
7a. If Yes in question 7 above, please provide event name(s) and date(s):
8. Have you ever received support or funding from the USOPC?
9. Have you ever served a period of Ineligibility for committing an anti-doping rule violation?
10. Are you an NCAA Student-Athlete?
Upcoming Competition Name(s) and Date(s)

TUE Pre-Check
Do I Need a TUE?

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Definitions

Read specific definitions of terms to help your Pre-Check submission

TUE Applications and Renewal Details
Apply for or Renew your TUE Here

If you determined that a Therapeutic Use Exemption (TUE) is needed or if your TUE is nearing it’s expiration date or has already expired, please follow the link below to complete and submit your TUE application or renewal.

Please note: any TUE application submitted to USADA without medical documentation will be returned to the athlete and will not be processed.

TUE Resources
Therapeutic Use Exemption Rules and Policy Details

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WHAT HAPPENS TO MY TUE?

TUE applications are reviewed by medical professionals who are members of an independent TUE Committee (TUEC), which must be comprised of medical experts with various areas of medical specialty, ranging from endocrinology to psychiatry. The USADA TUEC currently includes more than 20 medical professionals, many of whom are practicing physicians, work with athletes, and publish research in their field of specialty. Here’s what you need to know about the journey of a TUE, from the diagnosis to the TUE decision.

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Inhaler on table.

USADA’S TUE POLICY

USADA’s Policy for Therapeutic Use Exemptions is based upon the relevant provisions of the World Anti-Doping Code and the provisions of the World Anti-Doping Agency International Standard for Therapeutic Use Exemptions. This Policy outlines the full rules athletes and their support personnel must follow when a TUE is required.

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WADA’S INTERNATIONAL STANDARD ON THERAPEUTIC USE EXEMPTIONS

The purpose of the International Standard for Therapeutic Use Exemptions (ISTUE) is to ensure that the process of granting TUEs is harmonized across sports and countries. This policy balances the necessity for athletes to have access to important medication, while ensuring clean athletes the right to compete on a clean and level playing field.

Frequently Asked Questions

Find answers to commonly asked questions about Therapeutic Use Exemptions and the application process.

Click on the question to drop down the answer.

Do I need a Therapeutic Use Exemption (TUE) to use a prohibited substance / medication / method?

This will depend on your competition level (whether you are an international, national, recreational athlete or sport participant) and the Prohibited List category of the substance/medication/method you are taking. If you’re a Recreational/Non-competitive/Masters athlete but would like to participate in events and races sanctioned by a National Governing Body (e.g. USA Triathlon, USA Cycling, etc.) or a World Anti-Doping Code Signatory, please complete the USADA TUE Pre-Check Form.

Any athlete is encouraged to use the TUE Pre-Check Form. The TUE Pre-Check is an online form that allows USADA to evaluate if there is a need for a TUE based on your answers to specific questions. This helps athletes save time by determining whether a TUE is even necessary. We will respond to your TUE Pre-Check inquiry within three to five business days to let you know whether a TUE is required. If a TUE is necessary, we will direct you to specific TUE information related to your medication, so you understand what is required to submit a complete TUE application. If you’re submitting Whereabouts information to USADA or an International Federation, you can submit the TUE Pre-Check Form, but it is recommended you proceed directly to submitting a TUE application because of your classification as an athlete.

Please review the USADA Surgery Checklist to help determine the appropriate steps in preparing for your upcoming surgery.

Due to USADA and the NCAA having different anti-doping programs and rules, we do not recognize each other’s medical exemptions/TUEs at this time. If you are an NCAA athlete and you will be competing in an event sanctioned by a World Anti-Doping Code Signatory organization or are a member of those organizations like US National Governing Bodies, you may need to submit a TUE to USADA depending on your level of competition and the substance. If you are only competing within the NCAA and/or in NCAA sanctioned events (that are not co-sanctioned by a US National Governing Body) you will need to consult your Athletic Department Medical Staff regarding NCAA Medical Exceptions Procedures.

As soon as reasonably possible after the emergency treatment and medical situation has concluded:

  1. Collect all available medical documentation that completely outline the clinical exam, diagnosis, treatment plan, and any prohibited substances and methods administered (which may include ER admission/discharge notes, and a physician’s clinical notes detailing the treatment).
  2. Completely fill out a TUE application and write “EMERGENCY TUE” at the top of the form.
  3. Write a personal statement regarding the circumstances surrounding the events as they occurred along with any other relevant information.

Submit all three things (TUE application, medical notes, and personal statement) in accordance with any specific instructions related to your condition on the USADA TUE Application webpage to USADA.

All U.S. athletes are encouraged to submit their TUE application directly to USADA, even though in some instances, the International Federation is the review body for the TUE. If you are still unsure after your research, you can always submit your TUE application to USADA, and we will do our best to assist in determining which TUE authority is for you.

To apply for a TUE, please visit the USADA TUE Application page.

We request that athletes submit a TUE 30 days in advance of their planned use of any prohibited medication or method. Once a TUE application is received, USADA will respond within three to five business days whether the application is complete. If it is incomplete, we will send you a letter describing the deficiencies. Complete applications are sent to our TUE Committee (TUEC). The TUEC will render a decision as soon as possible and usually within no more than twenty-one (21) calendar days of receipt of a complete application (unless exceptional circumstances apply). Where a TUE application is made in a reasonable time prior to an event, the TUEC will attempt (but cannot guarantee) to issue a decision prior to an athlete’s scheduled event.

Potentially. First and foremost, we encourage athletes to consider their health first and athletic competition second. If you have a medical condition for which you have been prescribed a prohibited substance, medication, or method, consult with your medical provider. Depending on your competition level and the prohibited status of the substance, medication, or method, if you compete without a TUE, are tested, and your sample is positive for the prohibited substance, you could be at risk of having committed an anti-doping rule violation (ADRV), which may result in a sanction and public announcement. However, it may also be possible to receive a retroactive TUE depending on the circumstances.

If you compete while your TUE application is being processed, you could be at risk of an ADRV if your TUE is denied. TUEs are not guaranteed to be approved regardless of the reason or medical condition. A TUE approval prior to a competition is the safest course of action to follow.

Retroactive TUEs may be considered under any one of the following exceptions:

  1. Emergency or urgent treatment of a medical condition; or
  2. There was insufficient time, opportunity, or other exceptional circumstances that prevented submission prior to sample collection; or
  3. Due to prioritization of sports by the athlete’s NADO, the athlete was not required to get a TUE in advance; or
  4. Due to the athlete’s competitive status (not International-Level or National-Level), they are permitted to apply for a retroactive TUE; or
  5. The athlete used a substance/medication/method out-of-competition that is prohibited in-competition only.

Please call USADA directly if you have questions regarding a retroactive TUE and if it is appropriate for your specific situation.

If your TUE is approved, you will receive a certificate of approval along with an approval letter noting any conditions of the approval, as well as instructions for renewal. Please pay close attention to the conditions as, if these are not adhered to, could result in the cancellation of your TUE or denial of any TUE renewal. It is also important to be aware that if you’re competing internationally or in an International Federation (IF)-sanctioned event, that not all IFs will recognize a TUE decision issued by USADA. For this reason, it is very important you notify USADA if you intend to compete internationally. Please note “international events” can be held in the United States and not all events occurring in another country are considered “international events” for the purposes of TUEs. Finally, note the expiration date of the TUE and apply for a renewal at least 30 days in advance of the expiration date to ensure there are no gaps in your approval and you are not competing without a TUE.

Yes. While not mandatory, it would be beneficial to alert USADA of the existence of a TUE from another NADO/RADO/IF. If the TUE is approved in WADA’s database (known as ADAMS), USADA will be able to verify it. There is no need to resubmit to USADA unless we advise you otherwise.

The event organizer can help you determine if an event is a national or international-level competition. This information is often on the event website or in the registration materials. National Governing Bodies and International Federations are required by WADA to post their “sanctioned” competitions on their websites, as well. Please note, sometimes “international events” are held in the United States, and not all events occurring in another country are considered “international events” (e.g., sanctioned by the International Federation).

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